ODTX · NASDAQ · Biotechnology

Odyssey Therapeutics (ODTX)

Develops immune-signaling therapies for autoimmune and inflammatory diseases.

$27.90
Pre-market+1.29 (+4.83%)
At close$26.62(+8.63%)
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Odyssey Therapeutics, Inc.ODTXHealth Care

Develops small-molecule and protein therapeutics for autoimmune and inflammatory diseases, anchored by an oral RIPK2 scaffolding inhibitor in clinical development for inflammatory bowel disease. It is a pre-commercial, single-segment drug developer whose future product revenue depends on clinical success, approval, manufacturing, commercialization, reimbursement, and adoption.

Develops small-molecule and protein therapeutics against upstream immune-signaling nodes in autoimmune and inflammatory disease. Its oral RIPK2 scaffolding inhibitor is in clinical development for inflammatory bowel disease, while other disclosed programs target SLC15A4, TNFR2, TSLP/IL-33, IRAK4, and IRF5 for immune and respiratory conditions.

Selects targets with human genetics, clinical, or translational support, then combines immunobiology, chemistry, structural biology, genetics, pharmacology, and AI/ML models to choose an appropriate modality. Research and clinical development drive operations, with contract manufacturers supplying clinical materials.

Has no approved products, product-sales revenue, manufacturing facilities, or sales and marketing organization. Progress toward product revenue depends on clinical development, regulatory approval, third-party manufacturing, commercialization, reimbursement, and adoption.

Company facts

CEOGary D. Glick
ListedMay 8, 2026
ExchangeNASDAQ
HeadquartersBoston, MA
CountryUnited States
Employees100
CIK0001882782
ISINUS67613T1043

Market cap$1.28B
EPS (ttm)−$3.01
P/E (ttm)−8.85
ROE177.7%
P/B1.91
P/S0.00
Dividend yieldDiv yield
Beta

Price target$40.00+50.3%Avg of 2 analysts
ConsensusBuy2 of 2 analysts
Ratings

Target rangeAs of Sep 2, 2026

Latest analyst notes

DateFirmActionRatingTarget
Aug 27, 2026H.C. WainwrightInitiateBuy$44
Jun 2, 2026WedbushTarget$30
Jun 2, 2026OppenheimerTarget$40

Next report
Nov 4, 2026
estimated · in 62 days
EPS estimate
−$1.08
Revenue estimate
Fiscal quarter
Q3 FY26

EPSReportedEstimate

Jun '26Aug '26Nov '26
Reported−$6.75−$1.26Pending
Estimate−$0.83−$0.83−$1.08
Surprise−713.3%−51.8%

RevenueReportedEstimate

Jun '26Aug '26Nov '26
ReportedPending
Estimate
Surprise
Estimate−$1.08
ReportedDue Nov 4, 2026
Estimate
ReportedDue Nov 4, 2026
View details

Debt to equity5.90%
Current ratio1,136.10%

ProfitabilityRevenueNet incomeNet margin

Q1 FY26Q2 FY26
Revenue$0$0
Net income−$38.3M−$52.8M
Net margin

GrowthOperating income

Q1 FY26Q2 FY26
Operating income−$39.8M−$55.5M
YoY growth

Balance sheet, Jun 30, 2026Cash & short-term investments $310.6M · Total debt $24.8M · Total assets $483.9M · Shareholders' equity $421.2M

Revenue
$0
Operating income
−$55.5M
Net income
−$52.8M
View details

No dividends on record.

Institutions59 holders · as of Jun 30, 202672.70%34.92M shares
Otherremainder27.30%13.11M shares

48.03M company shares as of Aug 21, 2026 · institutions as of Jun 30, 2026 · holders as of their latest filing

The share count has not been confirmed by a second filing; stakes use it as it stands.

Top shareholders13F · 13D/G · Form 4

HolderStakeSharesEvidence
FMR LLCInstitution
10.78%5.18M13Fas of Jun 30, 2026
Sr One Capital Management, LPInstitution
7.90%3.79M13Fas of Jun 30, 2026
TPG GP A, LLCInstitution
7.68%3.69M13Fas of Jun 30, 2026
Lightspeed Management Company, L.L.C.Institution
7.51%3.61M13Fas of Jun 30, 2026
Orbimed Advisors LLCInstitution
6.25%3.00M13Fas of Jun 30, 2026
See all 25

13F — a manager's quarterly holdings

Insider tradesForm 4

Nothing filed in the last 12 months.

View details

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ComparePre-market

CompanyPriceChange
Odyssey Therapeutics$27.90+4.83%$1.28B
AbbVie$262.35+0.24%$462.37B73.717.27.2+10.2%
Johnson & Johnson$275.36+0.04%$663.23B31.923.16.8+6.6%
Takeda (ADR)$18.53+0.47%$58.65B51.256.72.0+5.8%
Eli Lilly$1,166.44+0.61%$1.09T38.928.413.7+47.7%
Pfizer$28.96−0.24%$165.40B38.310.42.6+2.6%
Bristol-Myers Squibb$67.50−0.23%$138.21B14.910.62.8+5.7%
Kymera Therapeutics$118.52−0.13%$9.76B92.9+466.4%
Median38.620.26.8+6.6%